What are the two main mechanisms for artery development?

Arteries develop via vasculogenesis and angiogenesis. Vasculogenesis involves angioblasts assembling into vessel precursors, while angiogenesis is sprouting from preexisting vessels.

What do the pharyngeal arch arteries become in adults?

The pharyngeal arch arteries transform into major head, neck, and thoracic arteries. For example, the third arch becomes common and internal carotid arteries, the fourth arch forms the right subclavian artery and arch of aorta, and the sixth arch develops into pulmonary arteries and ductus arteriosus.

How do limb arteries develop?

Upper limb arteries derive from the 7th cervical intersegmental artery, forming structures like the axillary and brachial arteries. Lower limb arteries arise from the 5th lumbar intersegmental artery, contributing to arteries such as the popliteal and femoral.

What are the branches of the dorsal aorta?

The dorsal aorta gives rise to three main branch types: posterolateral (somatic intersegmental) like intercostal arteries, lateral splanchnic like renal arteries, and ventral splanchnic like celiac artery.

What happens to umbilical arteries after birth?

Postnatally, umbilical arteries transform: the proximal part becomes the superior vesical artery, and the distal part regresses into the medial umbilical ligament.

What is patent ductus arteriosus (PDA)?

Patent ductus arteriosus is a clinical condition where the ductus arteriosus fails to close after birth, causing a left-to-right shunt. It is often treated with NSAIDs or surgery.

What is coarctation of the aorta?

Coarctation of the aorta is a narrowing near the ductus arteriosus. It can be preductal (associated with persistent ductus arteriosus) or postductal (more common in adults).

Aortic Arches – Development of Major Arteries

❓ Frequently Asked Questions