What are the main components of connective tissue?

Connective tissue consists of three essential components: ground substance, an amorphous gel-like base that permits diffusion; fibers, which provide tensile strength and structural framework; and cells, responsible for matrix production and immune functions.

What are the different types of fibers found in connective tissue?

There are three primary fiber types: collagen fibers, which are strong and flexible and found in bone, cartilage, tendons, and ligaments; elastic fibers, which stretch and recoil and are found in lungs, skin, and blood vessels; and reticular fibers, which are fine fibers forming supporting frameworks in organs like the liver and spleen. All are synthesized by fibroblasts.

What are the main functions of connective tissue?

Connective tissue primarily binds, supports, and integrates other tissues in the body. It also provides structural framework, permits diffusion, and plays roles in immune defense and energy storage.

What are the key cell types in connective tissue?

Connective tissue includes fixed cells like fibroblasts (synthesize matrix), macrophages (phagocytic), mast cells (involved in allergic responses), and adipocytes (store lipids). It also has free wandering immune cells such as neutrophils and lymphocytes.

How is connective tissue classified?

Connective tissue is classified into two main groups: connective tissue proper, which includes loose (areolar), dense regular, dense irregular, elastic, adipose, and reticular tissues; and specialized connective tissue, which includes bone, cartilage, and blood.

Where is loose connective tissue found and what does it do?

Loose (areolar) connective tissue is the most widespread type. It contains all fibers and cells in a semifluid matrix and functions to support vessels and nerves, and bind skin to deep fascia.

What are some clinical conditions related to connective tissue?

Clinical conditions include keloids (excess collagen in scars), osteogenesis imperfecta (genetic defect in type I collagen causing fragile bones), and vitamin C deficiency (impairs collagen formation and wound healing).

Connective Tissue – Cells, Fibers & Major Types

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